5JNT
Crystal structure of human low molecular weight protein tyrosine phosphatase (LMPTP) type A complexed with MES
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Low molecular weight phosphotyrosine protein phosphatase | polymer | 160 | 18237.7 | 1 | UniProt (P24666) Pfam (PF01451) In PDB | Homo sapiens (Human) | LMW-PTPase,Adipocyte acid phosphatase,Low molecular weight cytosolic acid phosphatase,Red cell acid phosphatase 1 |
| 2 | A | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
| 3 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 4 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 5 | water | water | 18.0 | 275 | Chemie (HOH) |
Sequence modifications
A: 0 - 157 (UniProt: P24666)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Val 4 | Ala 5 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18237.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 397.5 | |
| All* | Total formula weight | 18635.2 |
