5IS0
Structure of TRPV1 in complex with capsazepine, determined in lipid nanodisc
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | C, B, D, E | Transient receptor potential cation channel subfamily V member 1 | polymer | 636 | 72959.3 | 4 | UniProt (O35433) Pfam (PF00023) Pfam (PF00520) In PDB | Rattus norvegicus (Rat) | TrpV1, Capsaicin receptor, Osm-9-like TRP channel 1, OTRPC1, Vanilloid receptor 1, Vanilloid receptor type 1-like |
2 | C, B, D, E | capsazepine | non-polymer | 376.9 | 4 | Chemie (6ET) |
Sequence modifications
C, B, D, E: 110 - 603 (UniProt: O35433)
C, B, D, E: 627 - 764 (UniProt: O35433)
PDB | External Database | Details |
---|---|---|
Ala 106 | - | expression tag |
Met 107 | - | expression tag |
Gly 108 | - | expression tag |
Ser 109 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 291837.2 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1507.6 | |
All* | Total formula weight | 293344.8 |