5DYY
Crystal structure of human butyrylcholinesterase in complex with N-((1-benzylpiperidin-3-yl)methyl)naphthalene-2-sulfonamide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Cholinesterase | polymer | 530 | 59774.5 | 2 | UniProt (P06276) Pfam (PF00135) In PDB | Homo sapiens (Human) | Acylcholine acylhydrolase,Butyrylcholine esterase,Choline esterase II,Pseudocholinesterase |
2 | C | alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 367.3 | 1 | In PDB GlyTouCan (G86851RC) | |||
3 | D, F | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
4 | E | beta-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 367.3 | 1 | In PDB GlyTouCan (G61843VN) | |||
5 | G, H | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 2 | In PDB GlyTouCan (G28454KX) | |||
6 | A, B | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
7 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
8 | A, B | N-{[(3R)-1-benzylpiperidin-3-yl]methyl}naphthalene-2-sulfonamide | non-polymer | 394.5 | 2 | Chemie (5HH) | |||
9 | A, B | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
10 | B, A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 9 | Chemie (NAG) | |||
11 | water | water | 18.0 | 233 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 119549.0 | |
Branched | Number of molecules | 6 |
Total formula weight | 2724.6 | |
Non-Polymers* | Number of molecules | 21 |
Total formula weight | 3497.5 | |
All* | Total formula weight | 125771.1 |