5DYT

Crystal structure of human butyrylcholinesterase in complex with N-((1-benzylpiperidin-3-yl)methyl)-N-methylnaphthalene-2-sulfonamide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Cholinesterase	polymer	530	59774.5	2	UniProt (P06276) Pfam (PF00135) In PDB	Homo sapiens (Human)	Acylcholine acylhydrolase,Butyrylcholine esterase,Choline esterase II,Pseudocholinesterase
2	C, E, G	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	3	In PDB GlyTouCan (G21290RB)
3	D, F, H	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	3	In PDB GlyTouCan (G42666HT)
4	I	alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		367.3	1	In PDB GlyTouCan (G86851RC)
5	A, B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	8	Chemie (NAG)
6	B, A	N-{[(3R)-1-benzylpiperidin-3-yl]methyl}-N-methylnaphthalene-2-sulfonamide	non-polymer		408.6	2	Chemie (5HB)
7	B, A	GLYCEROL	non-polymer		92.1	5	Chemie (GOL)
8	B, A	1,2-ETHANEDIOL	non-polymer		62.1	4	Chemie (EDO)
9	B, A	UNKNOWN ATOM OR ION	non-polymer			6	Chemie (UNX)
10	B	beta-L-fucopyranose	non-polymer		164.2	1	Chemie (FUL)
11	B	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG)
12		water	water		18.0	232	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	119549.0
Branched	Number of molecules	7
	Total formula weight	3352.2
Non-Polymers*	Number of molecules	27
	Total formula weight	3565.8
All*	Total formula weight	126467.0

*Water molecules are not included.