5DK3
Crystal Structure of Pembrolizumab, a full length IgG4 antibody
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, F | Light Chain | polymer | 218 | 23768.4 | 2 | Homo sapiens | ||
| 2 | B, G | Heavy Chain | polymer | 444 | 49166.0 | 2 | Homo sapiens | ||
| 3 | C | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1317.2 | 1 | In PDB GlyTouCan (G39213VZ) | |||
| 4 | D | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1260.2 | 1 | In PDB GlyTouCan (G45889JQ) | |||
| 5 | E, H, I | beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose | branched | 342.3 | 3 | In PDB BIRD (PRD_900003) | sucrose | ||
| 6 | A, B | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 7 | water | water | 18.0 | 481 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 145869.0 | |
| Branched | Number of molecules | 5 |
| Total formula weight | 3604.3 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 480.3 | |
| All* | Total formula weight | 149953.6 |
