5BW2
X-ray crystal structure of Aplysia californica acetylcholine binding protein (Ac-AChBP) Y55W in complex with 2-Pyridin-3-yl-1-aza-bicyclo[2.2.2]octane; 2-(3-pyridyl)quinuclidine; 2-PQ (TI-4699)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E | Soluble acetylcholine receptor | polymer | 230 | 26235.1 | 5 | UniProt (Q8WSF8) Pfam (PF02931) In PDB | Aplysia californica (California sea hare) | |
2 | A, B, C, D | (2R)-2-(pyridin-3-yl)-1-azabicyclo[2.2.2]octane | non-polymer | 188.3 | 4 | Chemie (4VU) | |||
3 | water | water | 18.0 | 462 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 1 - 219 (UniProt: Q8WSF8)
PDB | External Database | Details |
---|---|---|
Asp -8 | - | expression tag |
Tyr -7 | - | expression tag |
Lys -6 | - | expression tag |
Asp -5 | - | expression tag |
Asp -4 | - | expression tag |
Asp -3 | - | expression tag |
Asp -2 | - | expression tag |
Lys -1 | - | expression tag |
Leu 0 | - | expression tag |
Trp 55 | Tyr 72 | engineered mutation |
Ser 220 | - | expression tag |
Arg 221 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 131175.7 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 753.1 | |
All* | Total formula weight | 131928.8 |