4Z7G

Crystal structure of human IRE1 cytoplasmic kinase-RNase region - apo

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Serine/threonine-protein kinase/endoribonuclease IRE1	polymer	416	47755.8	2	UniProt (O75460) Pfam (PF00069) Pfam (PF06479) In PDB	Homo sapiens (Human)	Endoplasmic reticulum-to-nucleus signaling 1,Inositol-requiring protein 1,hIRE1p,Ire1-alpha,IRE1a
2	A, B	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
3		water	water		18.0	15	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	95511.6
Non-Polymers*	Number of molecules	2
	Total formula weight	46.0
All*	Total formula weight	95557.6

*Water molecules are not included.