4XEV

Fusion of Pyk2-FAT domain with Leupaxin LD1 motif, complexed with Leupaxin LD4 peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D	Fusion protein of Protein-tyrosine kinase 2-beta FAT domain and Leupaxin LD1 motif	polymer	167	18034.4	2	UniProt (Q14289) Pfam (PF03623) In PDB	Homo sapiens (Human)
2	C, F	19-mer peptide containing Leupaxin LD4 motif	polymer	19	2090.4	2	UniProt (by SIFTS) (O60711) In PDB	Homo sapiens
3		water	water		18.0	71	Chemie (HOH)

Sequence modifications

A, D: 871 - 1005 (UniProt: Q14289)

PDB	External Database	Details
Gly 867	-	expression tag
Ser 868	-	expression tag
His 869	-	expression tag
Met 870	-	expression tag
Ser 899	Cys 899	engineered mutation
Ala 972	Cys 972	engineered mutation
Gly 1006	-	linker
Gly 1007	-	linker
Ser 1995	-	linker
Gly 1996	-	linker
Gly 1997	-	linker
Gly 1998	-	linker
Gly 1999	-	linker
Gly 2000	-	linker

A, D: 2001 - 2020 (PDB: 4XEV)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	40249.6
All*	Total formula weight	40249.6

*Water molecules are not included.