4XEV
Fusion of Pyk2-FAT domain with Leupaxin LD1 motif, complexed with Leupaxin LD4 peptide
Summary for 4XEV
| Entry DOI | 10.2210/pdb4xev/pdb |
| Related | 4XEF 4XEK |
| Descriptor | Fusion protein of Protein-tyrosine kinase 2-beta FAT domain and Leupaxin LD1 motif, 19-mer peptide containing Leupaxin LD4 motif (3 entities in total) |
| Functional Keywords | 4-helix bundle, focal adhesion, tyrosine kinase, leupaxin, cell adhesion |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 40249.63 |
| Authors | Miller, D.J. (deposition date: 2014-12-24, release date: 2015-12-30, Last modification date: 2023-09-27) |
| Primary citation | Vanarotti, M.S.,Finkelstein, D.B.,Guibao, C.D.,Nourse, A.,Miller, D.J.,Zheng, J.J. Structural Basis for the Interaction between Pyk2-FAT Domain and Leupaxin LD Repeats. Biochemistry, 55:1332-1345, 2016 Cited by PubMed: 26866573DOI: 10.1021/acs.biochem.5b01274 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.0073 Å) |
Structure validation
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