4X21
The MAP kinase JNK3 as target for halogen bonding
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Mitogen-activated protein kinase 10 | polymer | 367 | 42260.9 | 2 | UniProt (P53779) Pfam (PF00069) In PDB | Homo sapiens (Human) | MAPK 10,MAP kinase p49 3F12,Stress-activated protein kinase 1b,SAPK1b,Stress-activated protein kinase JNK3,c-Jun N-terminal kinase 3 |
| 2 | A, B | N-ethyl-4-{[4-(1H-indol-3-yl)-5-iodopyrimidin-2-yl]amino}piperidine-1-carboxamide | non-polymer | 490.3 | 2 | Chemie (3WH) | |||
| 3 | A, B | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 4 | water | water | 18.0 | 342 | Chemie (HOH) |
Sequence modifications
A, B: 39 - 402 (UniProt: P53779)
| PDB | External Database | Details |
|---|---|---|
| Gly 36 | - | expression tag |
| Gly 37 | - | expression tag |
| Ser 38 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 84521.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1051.6 | |
| All* | Total formula weight | 85573.3 |
