Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004707 | molecular_function | MAP kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004707 | molecular_function | MAP kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue 3WH A 501 |
| Chain | Residue |
| A | VAL78 |
| A | LEU206 |
| A | HOH682 |
| A | HOH773 |
| A | ALA91 |
| A | MET146 |
| A | GLU147 |
| A | MET149 |
| A | ASP150 |
| A | ALA151 |
| A | ASN152 |
| A | GLN155 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue CL A 502 |
| Chain | Residue |
| A | ARG227 |
| A | ASP267 |
| A | TYR268 |
| B | ASP200 |
| B | HOH661 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue CL B 502 |
| Chain | Residue |
| B | GLU242 |
| B | ASN243 |
| B | SER349 |
| B | VAL350 |
| B | HOH624 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | binding site for Di-peptide 3WH B 501 and MET B 146 |
| Chain | Residue |
| B | SER72 |
| B | VAL78 |
| B | VAL90 |
| B | ALA91 |
| B | LYS93 |
| B | LEU144 |
| B | VAL145 |
| B | GLU147 |
| B | LEU148 |
| B | MET149 |
| B | ALA151 |
| B | ASN152 |
| B | GLN155 |
Functional Information from PROSITE/UniProt
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IiHrDLKpsNIVV |
| Chain | Residue | Details |
| A | ILE185-VAL197 | |
| site_id | PS01351 |
| Number of Residues | 103 |
| Details | MAPK MAP kinase signature. FqnqthakrayRElvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqviqmeldhermsyllyqmlcgikhlhsagiih..........RDlKpsnivvksdC |
| Chain | Residue | Details |
| A | PHE99-CYS201 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton acceptor |
| Chain | Residue | Details |
| A | ASP189 | |
| B | ASP189 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: |
| Chain | Residue | Details |
| B | ILE70 | |
| B | LYS93 | |
| A | ILE70 | |
| A | LYS93 | |
| Chain | Residue | Details |
| A | THR221 | |
| B | THR221 | |
| Chain | Residue | Details |
| A | TYR223 | |
| B | TYR223 | |
