4RUO
Crystal structure of zVDR L337H mutant-gemini complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | X | Vitamin D3 receptor A | polymer | 302 | 34085.7 | 1 | UniProt (Q9PTN2) Pfam (PF00104) In PDB | Danio rerio (leopard danio zebra danio zebra fish) | VDR-A, 1,25-dihydroxyvitamin D3 receptor A, Nuclear receptor subfamily 1 group I member 1-A |
| 2 | B | Nuclear receptor coactivator 2 | polymer | 13 | 1579.9 | 1 | UniProt (Q15596) In PDB | Homo sapiens | NCoA-2, Class E basic helix-loop-helix protein 75, bHLHe75, Transcriptional intermediary factor 2, hTIF2 |
| 3 | X | 21-NOR-9,10-SECOCHOLESTA-5,7,10(19)-TRIENE-1,3,25-TRIOL, 20-(4-HYDROXY-4-METHYLPENTYL)-, (1A,3B,5Z,7E) | non-polymer | 502.8 | 1 | Chemie (BIV) | |||
| 4 | water | water | 18.0 | 11 | Chemie (HOH) |
Sequence modifications
X: 156 - 453 (UniProt: Q9PTN2)
| PDB | External Database | Details |
|---|---|---|
| Gly 152 | - | expression tag |
| Ser 153 | - | expression tag |
| His 154 | - | expression tag |
| Met 155 | - | expression tag |
| His 337 | Leu 337 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35665.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 502.8 | |
| All* | Total formula weight | 36168.3 |
