4RUO
Crystal structure of zVDR L337H mutant-gemini complex
Summary for 4RUO
Entry DOI | 10.2210/pdb4ruo/pdb |
Related | 2HC4 2HCD 4RUJ 4RUP |
Descriptor | Vitamin D3 receptor A, Nuclear receptor coactivator 2, 21-NOR-9,10-SECOCHOLESTA-5,7,10(19)-TRIENE-1,3,25-TRIOL, 20-(4-HYDROXY-4-METHYLPENTYL)-, (1A,3B,5Z,7E), ... (4 entities in total) |
Functional Keywords | alpha helical sandwich, transcription factor, retinoid x receptor, ligand, dna, phosphorylation, nucleus, transcription factor-transcription regulator complex, transcription factor/transcription regulator |
Biological source | Danio rerio (leopard danio,zebra danio,zebra fish) More |
Total number of polymer chains | 2 |
Total formula weight | 36168.30 |
Authors | Huet, T.,Moras, D.,Rochel, N. (deposition date: 2014-11-21, release date: 2015-10-07, Last modification date: 2024-02-28) |
Primary citation | Huet, T.,Laverny, G.,Ciesielski, F.,Molnar, F.,Ramamoorthy, T.G.,Belorusova, A.Y.,Antony, P.,Potier, N.,Metzger, D.,Moras, D.,Rochel, N. A vitamin D receptor selectively activated by gemini analogs reveals ligand dependent and independent effects. Cell Rep, 10:516-526, 2015 Cited by PubMed: 25620699DOI: 10.1016/j.celrep.2014.12.045 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.805 Å) |
Structure validation
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