4ROJ
Crystal Structure of the VAV2 SH2 domain in complex with TXNIP phosphorylated peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Guanine nucleotide exchange factor VAV2 | polymer | 117 | 13758.4 | 3 | UniProt (P52735) Pfam (PF00017) In PDB | Homo sapiens (human) | VAV-2 |
| 2 | D, E, F | Thioredoxin-interacting protein | polymer | 14 | 1439.6 | 3 | UniProt (Q9H3M7) In PDB | Homo sapiens | Thioredoxin-binding protein 2, Vitamin D3 up-regulated protein 1 |
| 3 | A, B, C, F | UNKNOWN ATOM OR ION | non-polymer | 14 | Chemie (UNX) | ||||
| 4 | water | water | 18.0 | 145 | Chemie (HOH) |
Sequence modifications
A, B, C: 667 - 782 (UniProt: P52735)
D, E, F: 327 - 338 (UniProt: Q9H3M7)
| PDB | External Database | Details |
|---|---|---|
| Gly 666 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ace 326 | - | expression tag |
| Nh2 339 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 45594.0 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 0.0 | |
| All* | Total formula weight | 45594.0 |
