4R2P
Wilms Tumor Protein (WT1) zinc fingers in complex with hydroxymethylated DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Wilms tumor protein, isoform 4/CRA_a | polymer | 93 | 11282.9 | 1 | UniProt (P19544) Pfam (PF00096) In PDB | Homo sapiens (human) | WT33 |
| 2 | B | DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*(5HC)P*GP*T)-3') | polymer | 11 | 3460.3 | 1 | synthetic construct | ||
| 3 | C | DNA (5'-D(*TP*AP*(5HC)P*GP*CP*CP*CP*AP*CP*GP*C)-3') | polymer | 11 | 3309.2 | 1 | synthetic construct | ||
| 4 | A | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 5 | A, C | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 6 | water | water | 18.0 | 143 | Chemie (HOH) |
Sequence modifications
A: 350 - 437 (UniProt: P19544)
| PDB | External Database | Details |
|---|---|---|
| Gly 345 | - | expression tag |
| Pro 346 | - | expression tag |
| Leu 347 | - | expression tag |
| Gly 348 | - | expression tag |
| Ser 349 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 18052.3 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 320.4 | |
| All* | Total formula weight | 18372.7 |
