4ORX
Three-dimensional structure of the C65A-K59A double mutant of Human lipocalin-type Prostaglandin D Synthase holo-form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Prostaglandin-H2 D-isomerase | polymer | 190 | 20959.6 | 2 | UniProt (P41222) Pfam (PF00061) In PDB | Homo sapiens (human) | Beta-trace protein, Cerebrin-28, Glutathione-independent PGD synthase, Lipocalin-type prostaglandin-D synthase, Prostaglandin-D2 synthase, PGD2 synthase, PGDS, PGDS2 |
| 2 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | B | 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL | non-polymer | 1221.5 | 1 | Chemie (PEU) | |||
| 4 | water | water | 18.0 | 106 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 190 (UniProt: P41222)
| PDB | External Database | Details |
|---|---|---|
| Ala 59 | Lys 59 | ENGINEERED MUTATION |
| Ala 65 | Cys 65 | ENGINEERED MUTATION |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 41919.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1317.5 | |
| All* | Total formula weight | 43236.8 |
