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4O5K

Structure of human DNA polymerase complexed with N7MG in the template base paired with incoming non-hydrolyzable CTP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1TDNA (5'-D(*CP*CP*GP*AP*CP*(FMG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3')polymer164877.21synthetic construct
2PDNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3')polymer103085.01synthetic construct
3DDNA (5'-D(P*GP*TP*CP*GP*G)-3')polymer51536.01synthetic construct
4ADNA polymerase betapolymer32637182.41UniProt (P06746)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
In PDB
Homo sapiens (human)
5AMAGNESIUM IONnon-polymer24.32Chemie (MG)
6ASODIUM IONnon-polymer23.02Chemie (NA)
7A2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidinenon-polymer466.21Chemie (0KX)
8waterwater18.0164Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight46680.6
Non-Polymers*Number of molecules5
Total formula weight560.8
All*Total formula weight47241.4
*Water molecules are not included.

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PDB entries from 2024-06-12

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