4NRE
The structure of human 15-lipoxygenase-2 with a substrate mimic
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Arachidonate 15-lipoxygenase B | polymer | 696 | 78104.9 | 1 | UniProt (O15296) Pfam (PF01477) Pfam (PF00305) In PDB | Homo sapiens (human) | 15-LOX-B, 15-lipoxygenase 2, 15-LOX-2, Arachidonate 15-lipoxygenase type II, Linoleate 13-lipoxygenase 15-LOb |
| 2 | A | FE (II) ION | non-polymer | 55.8 | 1 | Chemie (FE2) | |||
| 3 | A | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE | non-polymer | 306.4 | 2 | Chemie (C8E) | |||
| 4 | A | SULFATE ION | non-polymer | 96.1 | 12 | Chemie (SO4) | |||
| 5 | A | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 6 | A | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 7 | water | water | 18.0 | 368 | Chemie (HOH) |
Sequence modifications
A: 1 - 676 (UniProt: O15296)
| PDB | External Database | Details |
|---|---|---|
| Met -19 | - | expression tag |
| Gly -18 | - | expression tag |
| Ser -17 | - | expression tag |
| Ser -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Gly -7 | - | expression tag |
| Leu -6 | - | expression tag |
| Val -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Arg -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 78104.9 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 2177.9 | |
| All* | Total formula weight | 80282.8 |
