4NJD
Structure of p21-activated kinase 4 with a novel inhibitor KY-04031
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Serine/threonine-protein kinase PAK 4 | polymer | 296 | 33424.8 | 1 | UniProt (O96013) Pfam (PF00069) In PDB | Homo sapiens (human) | p21-activated kinase 4, PAK-4 |
2 | A | N-(1H-indazol-5-yl)-N'-[2-(1H-indol-3-yl)ethyl]-6-methoxy-1,3,5-triazine-2,4-diamine | non-polymer | 400.4 | 1 | Chemie (NJD) | |||
3 | water | water | 18.0 | 43 | Chemie (HOH) |
Sequence modifications
A: 300 - 591 (UniProt: O96013)
PDB | External Database | Details |
---|---|---|
Gly 296 | - | expression tag |
Ser 297 | - | expression tag |
His 298 | - | expression tag |
Met 299 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 33424.8 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 400.4 | |
All* | Total formula weight | 33825.3 |