4L6P

Structure of C22Y Mutant PCNA protein defective in DNA mismatch repair

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	Proliferating cell nuclear antigen	polymer	264	29833.0	3	UniProt (P15873) Pfam (PF00705) Pfam (PF02747) In PDB	Saccharomyces cerevisiae S288c (Baker's yeast)	PCNA
2	C	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
3		water	water		18.0	73	Chemie (HOH)

Sequence modifications

A, B, C: 1 - 258 (UniProt: P15873)

PDB	External Database	Details
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Tyr 22	Cys 22	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	89498.9
Non-Polymers*	Number of molecules	2
	Total formula weight	184.2
All*	Total formula weight	89683.1

*Water molecules are not included.