4K99
Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -pppdG(2 ,5 )pdG
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Cyclic GMP-AMP synthase | polymer | 362 | 42512.1 | 1 | UniProt (Q8C6L5) Pfam (PF03281) Pfam (PF20266) In PDB | Mus musculus (mouse) | cGAMP synthase, cGAS, m-cGAS, Mab-21 domain-containing protein 1 |
2 | D | DNA-F | polymer | 17 | 5253.5 | 1 | |||
3 | E | DNA-R | polymer | 17 | 5159.3 | 1 | |||
4 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
5 | A | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
6 | A | 3'-DEOXY-GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (GH3) | |||
7 | A | 3'-deoxy-guanosine 5'-monophosphate | non-polymer | 347.2 | 1 | Chemie (GDO) | |||
8 | water | water | 18.0 | 314 | Chemie (HOH) |
Sequence modifications
A: 147 - 507 (UniProt: Q8C6L5)
PDB | External Database | Details |
---|---|---|
Ser 146 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 52924.9 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 968.4 | |
All* | Total formula weight | 53893.3 |