4JIK
X-RAY Crystal structure of compound 22a (R)-2-(4-chlorophenyl)-8-(piperidin-3-ylamino)imidazo[1,2-c]pyrimidine-5-carboxamide bound to human chk1 kinase domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Serine/threonine-protein kinase Chk1 | polymer | 273 | 31455.2 | 1 | UniProt (O14757) Pfam (PF00069) In PDB | Homo sapiens (human) | CHK1 checkpoint homolog, Cell cycle checkpoint kinase, Checkpoint kinase-1 |
| 2 | A | 2-(4-chlorophenyl)-8-[(3S)-piperidin-3-ylamino]imidazo[1,2-c]pyrimidine-5-carboxamide | non-polymer | 370.8 | 1 | Chemie (1KO) | |||
| 3 | water | water | 18.0 | 169 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31455.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 370.8 | |
| All* | Total formula weight | 31826.1 |
