4I85

Crystal structure of transthyretin in complex with CHF5074 at neutral pH

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Transthyretin	polymer	127	13777.4	2	UniProt (P02766) Pfam (PF00576) In PDB	Homo sapiens (human)	ATTR, Prealbumin, TBPA
2	A, B	1-(3',4'-dichloro-2-fluorobiphenyl-4-yl)cyclopropanecarboxylic acid	non-polymer		325.2	2	Chemie (H50)
3		water	water		18.0	197	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	27554.7
Non-Polymers*	Number of molecules	2
	Total formula weight	650.3
All*	Total formula weight	28205.0

*Water molecules are not included.