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4FNC

Human TDG in a post-reactive complex with 5-hydroxymethyluracil (5hmU)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AG/T mismatch-specific thymine DNA glycosylasepolymer20423070.71UniProt (Q13569)
Pfam (PF03167)
In PDB
Homo sapiens (human)Thymine-DNA glycosylase
2CDNA (28-MER)polymer288646.61
3DDNA (29-MER)polymer298777.61
4A5-HYDROXYMETHYL URACILnon-polymer142.11Chemie (HMU)
5waterwater18.038Chemie (HOH)
Sequence modifications
A: 111 - 308 (UniProt: Q13569)
PDBExternal DatabaseDetails
Gly 105-expression tag
Ser 106-expression tag
His 107-expression tag
Met 108-expression tag
Ala 109-expression tag
Ser 110-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight40494.9
Non-Polymers*Number of molecules1
Total formula weight142.1
All*Total formula weight40637.0
*Water molecules are not included.

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PDB entries from 2024-04-24

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