4EFE

crystal structure of DNA ligase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	DNA ligase	polymer	331	37933.6	1	UniProt (Q837V6) Pfam (PF01653) In PDB	Enterococcus faecalis	Polydeoxyribonucleotide synthase [NAD(+)]
2	A	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
3	A	BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE	non-polymer		335.2	1	Chemie (NMN)
4	A	[4-amino-2-{[(1S,2R)-2-methylcyclohexyl]oxy}-5-oxopyrido[2,3-d]pyrimidin-8(5H)-yl]acetonitrile	non-polymer		313.4	1	Chemie (0OV)
5		water	water		18.0	461	Chemie (HOH)

Sequence modifications

A: 1 - 323 (UniProt: Q837V6)

PDB	External Database	Details
Leu 324	-	expression tag
Glu 325	-	expression tag
His 326	-	expression tag
His 327	-	expression tag
His 328	-	expression tag
His 329	-	expression tag
His 330	-	expression tag
His 331	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	37933.6
Non-Polymers*	Number of molecules	4
	Total formula weight	840.7
All*	Total formula weight	38774.3

*Water molecules are not included.