4EEF
Crystal structure of the designed inhibitor protein F-HB80.4 in complex with the 1918 influenza virus hemagglutinin.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E | Hemagglutinin HA1 chain | polymer | 331 | 36452.8 | 3 | UniProt (Q9WFX3) Pfam (PF00509) In PDB | Influenza A virus | Hemagglutinin HA1 chain |
| 2 | B, D, F | Hemagglutinin HA2 chain | polymer | 179 | 20394.4 | 3 | UniProt (Q9WFX3) Pfam (PF00509) In PDB | Influenza A virus | Hemagglutinin HA2 chain |
| 3 | G, H, I | F-HB80.4, DESIGNED HEMAGGLUTININ BINDING PROTEIN | polymer | 74 | 8810.8 | 3 | Artificial Gene | ||
| 4 | J, K, L | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
| 5 | water | water | 18.0 | 139 | Chemie (HOH) |
Sequence modifications
A, C, E: 7 - 329 (UniProt: Q9WFX3)
B, D, F: 1 - 176 (UniProt: Q9WFX3)
| PDB | External Database | Details |
|---|---|---|
| Asp 8 | Thr 15 | conflict |
| Pro 9 | Asn 16 | conflict |
| Gly 10 | Ala 17 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ser 177 | - | expression tag |
| Gly 178 | - | expression tag |
| Arg 179 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 196974.0 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1759.6 | |
| All* | Total formula weight | 198733.6 |
