4E3C
X-ray crystal structure of human IKK2 in an active conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | Inhibitor of nuclear factor kappa-B kinase subunit beta | polymer | 669 | 77163.5 | 6 | UniProt (O14920) Pfam (PF00069) Pfam (PF18397) In PDB | Homo sapiens (human) | I-kappa-B-kinase beta, IKK-B, IKK-beta, IkBKB, I-kappa-B kinase 2, IKK2, Nuclear factor NF-kappa-B inhibitor kinase beta, NFKBIKB |
Sequence modifications
A, B, C, D, E, F: 11 - 669 (UniProt: O14920)
| PDB | External Database | Details |
|---|---|---|
| Asn 1 | - | expression tag |
| Leu 2 | - | expression tag |
| Tyr 3 | - | expression tag |
| Phe 4 | - | expression tag |
| Gln 5 | - | expression tag |
| Gly 6 | - | expression tag |
| Ala 7 | - | expression tag |
| Met 8 | - | expression tag |
| Gly 9 | - | expression tag |
| Ser 10 | - | expression tag |
| Glu 177 | Ser 177 | engineered mutation |
| Glu 181 | Ser 181 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 462981.1 | |
| All* | Total formula weight | 462981.1 |
