4E3C

X-ray crystal structure of human IKK2 in an active conformation

Summary for 4E3C

• Entry DOI: 10.2210/pdb4e3c/pdb
• Descriptor: Inhibitor of nuclear factor kappa-B kinase subunit beta (1 entity in total)
• Functional Keywords: kanase, auto-phosphorylation, nemo binding, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: O14920
• Total number of polymer chains: 6
• Total formula weight: 462981.14

Authors

Polley, S.,Huang, D.B.,Hauenstein, A.V.,Ghosh, G.,Huxford, T. (deposition date: 2012-03-09, release date: 2013-06-19, Last modification date: 2023-09-13)

• Primary citation: Polley, S.,Huang, D.B.,Hauenstein, A.V.,Fusco, A.J.,Zhong, X.,Vu, D.,Hoffmann, A.,Verma, I.V.,Ghosh, G.,Huaford, T.; X-ray crystal structure of human IKK2 in an active conformation; Plos.Biol., 2013

Experimental method

X-RAY DIFFRACTION (3.98 Å)