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4B9T

Structure of the high fidelity DNA polymerase I with an oxidative formamidopyrimidine-dG DNA lesion -dC basepair in the post-insertion site.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ADNA POLYMERASEpolymer61970446.61UniProt (E1C9K5)
Pfam (PF00476)
In PDB
GEOBACILLUS STEAROTHERMOPHILUSDNA POLYMERASE I
2B5'-D(*AP*CP*CP*TP*GP*AP*CP*TP*CP*TP)-3'polymer113310.21GEOBACILLUS STEAROTHERMOPHILUS
3C5'-D(*CP*AP*TP*FOXP*AP*GP*AP*GP*TP*CP*AP*GP*GP*TP*TP)-3'polymer154644.11GEOBACILLUS STEAROTHERMOPHILUS
4AMAGNESIUM IONnon-polymer24.31Chemie (MG)
5ASULFATE IONnon-polymer96.12Chemie (SO4)
6waterwater18.059Chemie (HOH)
Sequence modifications
A: 297 - 876 (UniProt: E1C9K5)
PDBExternal DatabaseDetails
Met 258-expression tag
Ala 259-expression tag
Ser 260-expression tag
Trp 261-expression tag
Ser 262-expression tag
His 263-expression tag
Pro 264-expression tag
Gln 265-expression tag
Phe 266-expression tag
Glu 267-expression tag
Lys 268-expression tag
Gly 269-expression tag
Ala 270-expression tag
Ser 271-expression tag
Thr 272-expression tag
Ser 273-expression tag
Leu 274-expression tag
Tyr 275-expression tag
Lys 276-expression tag
Lys 277-expression tag
Ala 278-expression tag
Gly 279-expression tag
Ser 280-expression tag
Ala 281-expression tag
Ala 282-expression tag
Ala 283-expression tag
Val 284-expression tag
Leu 285-expression tag
Glu 286-expression tag
Glu 287-expression tag
Asn 288-expression tag
Leu 289-expression tag
Tyr 290-expression tag
Phe 291-expression tag
Gln 292-expression tag
Gly 293-expression tag
Ser 294-expression tag
Phe 295-expression tag
Thr 296-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight78400.8
Non-Polymers*Number of molecules3
Total formula weight216.4
All*Total formula weight78617.3
*Water molecules are not included.

220472

PDB entries from 2024-05-29

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