4AQ3
HUMAN BCL-2 WITH PHENYLACYLSULFONAMIDE INHIBITOR
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | APOPTOSIS REGULATOR BCL-2, BCL-2-LIKE PROTEIN 1 | polymer | 169 | 19509.7 | 6 | UniProt (P10415) UniProt (Q07817) Pfam (PF02180) Pfam (PF00452) In PDB | HOMO SAPIENS (HUMAN) | BCL2-L-1, APOPTOSIS REGULATOR BCL-X |
2 | A, B, C, D, E... | N,N-dibutyl-4-chloranyl-1-[2-(3,4-dihydro-1H-isoquinolin-2-ylcarbonyl)-4-[(7-iodanylnaphthalen-2-yl)sulfonylcarbamoyl]phenyl]-5-methyl-pyrazole-3-carboxamide | non-polymer | 866.2 | 6 | Chemie (398) |
Sequence modifications
A, B, C, D, E, F: 1 - 33 (UniProt: P10415)
A, B, C, D, E, F: 51 - 166 (UniProt: P10415)
A, B, C, D, E, F: 35 - 50 (UniProt: Q07817)
PDB | External Database | Details |
---|---|---|
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Asp 34 | - | expression tag |
Ala 55 | Thr 96 | variant |
Gly 69 | Arg 110 | variant |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 117058.0 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 5197.2 | |
All* | Total formula weight | 122255.2 |