3W8J

Crystal structure of P5 a0 in a complex with Prx4 c-term

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Protein disulfide-isomerase A6	polymer	142	15636.5	2	UniProt (Q15084) Pfam (PF00085) In PDB	Homo sapiens (human)	Endoplasmic reticulum protein 5, ER protein 5, ERp5, Protein disulfide isomerase P5, Thioredoxin domain-containing protein 7
2	C, D	C-terminal peptide from Peroxiredoxin-4	polymer	20	2092.3	2	UniProt (O08807) Pfam (PF10417) In PDB	Mus musculus	Antioxidant enzyme AOE372, Peroxiredoxin IV, Prx-IV, Thioredoxin peroxidase AO372, Thioredoxin-dependent peroxide reductase A0372
3	A, B	POTASSIUM ION	non-polymer		39.1	4	Chemie (K)
4	B	GLYCEROL	non-polymer		92.1	4	Chemie (GOL)
5		water	water		18.0	62	Chemie (HOH)

Sequence modifications

A, B: 20 - 140 (UniProt: Q15084)

PDB	External Database	Details
Met -1	-	EXPRESSION TAG
Gly 0	-	EXPRESSION TAG
Ser 1	-	EXPRESSION TAG
Ser 2	-	EXPRESSION TAG
His 3	-	EXPRESSION TAG
His 4	-	EXPRESSION TAG
His 5	-	EXPRESSION TAG
His 6	-	EXPRESSION TAG
His 7	-	EXPRESSION TAG
His 8	-	EXPRESSION TAG
Ser 9	-	EXPRESSION TAG
Ser 10	-	EXPRESSION TAG
Gly 11	-	EXPRESSION TAG
Leu 12	-	EXPRESSION TAG
Val 13	-	EXPRESSION TAG
Pro 14	-	EXPRESSION TAG
Arg 15	-	EXPRESSION TAG
Gly 16	-	EXPRESSION TAG
Ser 17	-	EXPRESSION TAG
His 18	-	EXPRESSION TAG
Met 19	-	EXPRESSION TAG
Ala 58	Cys 58	ENGINEERED MUTATION

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	35457.7
Non-Polymers*	Number of molecules	8
	Total formula weight	524.8
All*	Total formula weight	35982.4

*Water molecules are not included.