Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003756 | molecular_function | protein disulfide isomerase activity |
| B | 0003756 | molecular_function | protein disulfide isomerase activity |
| C | 0051920 | molecular_function | peroxiredoxin activity |
| D | 0051920 | molecular_function | peroxiredoxin activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE K A 201 |
| Chain | Residue |
| A | TYR21 |
| A | GLU49 |
| A | ALA58 |
| A | THR62 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE K A 202 |
| Chain | Residue |
| A | SER22 |
| A | ASP25 |
| A | VAL27 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 201 |
| Chain | Residue |
| B | GLU121 |
| B | ALA122 |
| B | ASP125 |
| B | ILE40 |
| B | ASN109 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL B 202 |
| Chain | Residue |
| A | GLN41 |
| B | ASP137 |
| B | HOH330 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 203 |
| Chain | Residue |
| B | ALA83 |
| B | VAL95 |
| B | PHE98 |
| D | GLY5 |
| D | HOH102 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL B 204 |
| Chain | Residue |
| B | GLN96 |
| D | HOH102 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE K B 205 |
| Chain | Residue |
| B | LEU20 |
| B | TYR21 |
| B | GLU49 |
| B | ALA58 |
| B | THR62 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE K B 206 |
| Chain | Residue |
| B | SER22 |
| B | SER23 |
| B | ASP25 |
| B | VAL27 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Nucleophile => ECO:0000250 |
| Chain | Residue | Details |
| A | CYS55 | |
| A | ALA58 | |
| B | CYS55 | |
| B | ALA58 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | SITE: Contributes to redox potential value => ECO:0000250 |
| Chain | Residue | Details |
| A | GLY56 | |
| A | HIS57 | |
| B | GLY56 | |
| B | HIS57 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Lowers pKa of C-terminal Cys of first active site => ECO:0000250 |
| Chain | Residue | Details |
| A | ARG118 | |
| B | ARG118 | |
| Chain | Residue | Details |
| A | SER129 | |
| B | SER129 | |
