3QIO
Crystal Structure of HIV-1 RNase H with engineered E. coli loop and N-hydroxy quinazolinedione inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Gag-Pol polyprotein,Ribonuclease HI,Gag-Pol polyprotein | polymer | 150 | 16921.5 | 1 | UniProt (P04585) UniProt (P0A7Y4) Pfam (PF00075) In PDB | Human immunodeficiency virus type 1 group M subtype B (HIV-1) | Pr160Gag-Pol,RNase HI,Ribonuclease H,RNase H,Pr160Gag-Pol |
| 2 | A | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 3 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | A | 3-hydroxy-6-(phenylsulfonyl)quinazoline-2,4(1H,3H)-dione | non-polymer | 318.3 | 1 | Chemie (QID) | |||
| 5 | water | water | 18.0 | 185 | Chemie (HOH) |
Sequence modifications
A: 427 - 506 (UniProt: P04585)
A: 79 - 102 (UniProt: P0A7Y4)
A: 517 - 561 (UniProt: P04585)
| PDB | External Database | Details |
|---|---|---|
| Met 426 | - | initiating methionine |
A: 517 - 561 (UniProt: P04585)
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 16921.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 524.2 | |
| All* | Total formula weight | 17445.7 |
