3Q03
Crystal structure of plasminogen activator inhibitor-1 in a metastable active conformation.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Plasminogen activator inhibitor 1 | polymer | 379 | 42780.0 | 2 | UniProt (P05121) Pfam (PF00079) In PDB | Homo sapiens (human) | PAI, PAI-1, Endothelial plasminogen activator inhibitor, Serpin E1 |
| 2 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | A, B | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 4 | water | water | 18.0 | 201 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 379 (UniProt: P05121)
| PDB | External Database | Details |
|---|---|---|
| Phe 175 | Trp 198 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 85560.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 201.7 | |
| All* | Total formula weight | 85761.8 |
