3OHT

Crystal Structure of Salmo Salar p38alpha

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	p38a	polymer	389	44958.0	2	UniProt (A9UJZ9) Pfam (PF00069) In PDB	Salmo salar (Atlantic salmon)
2	A, B	N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE	non-polymer		488.0	4	Chemie (1N1)
3	B	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
4		water	water		18.0	107	Chemie (HOH)

Sequence modifications

A, B: 1 - 361 (UniProt: A9UJZ9)

PDB	External Database	Details
Met -27	-	expression tag
Ser -26	-	expression tag
Tyr -25	-	expression tag
Tyr -24	-	expression tag
His -23	-	expression tag
His -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
Leu -17	-	expression tag
Glu -16	-	expression tag
Ser -15	-	expression tag
Thr -14	-	expression tag
Ser -13	-	expression tag
Leu -12	-	expression tag
Tyr -11	-	expression tag
Lys -10	-	expression tag
Lys -9	-	expression tag
Ala -8	-	expression tag
Gly -7	-	expression tag
Ser -6	-	expression tag
Ala -5	-	expression tag
Ala -4	-	expression tag
Ala -3	-	expression tag
Pro -2	-	expression tag
Phe -1	-	expression tag
Thr 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	89916.0
Non-Polymers*	Number of molecules	6
	Total formula weight	2144.2
All*	Total formula weight	92060.1

*Water molecules are not included.