3K3N

Crystal structure of the catalytic core domain of human PHF8

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	PHD finger protein 8	polymer	371	43279.3	1	UniProt (Q5JPR9) Pfam (PF02373) Pfam (PF17811) UniProt (by SIFTS) (Q9UPP1) In PDB	Homo sapiens (human)	PHF8
2	A	FE (II) ION	non-polymer		55.8	1	Chemie (FE2)
3		water	water		18.0	111	Chemie (HOH)

Sequence modifications

A: 86 - 447 (UniProt: Q5JPR9)

PDB	External Database	Details
Met 85	-	expression tag
Leu 448	-	expression tag
Glu 449	-	expression tag
His 450	-	expression tag
His 451	-	expression tag
His 452	-	expression tag
His 453	-	expression tag
His 454	-	expression tag
His 455	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	43279.3
Non-Polymers*	Number of molecules	1
	Total formula weight	55.8
All*	Total formula weight	43335.2

*Water molecules are not included.