3K3N
Crystal structure of the catalytic core domain of human PHF8
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FE2 A 1 |
| Chain | Residue |
| A | HOH8 |
| A | HOH19 |
| A | HOH43 |
| A | HIS247 |
| A | ASP249 |
| A | HIS319 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | GLU280 | |
| A | CYS300 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00538, ECO:0000269|PubMed:20023638, ECO:0000269|PubMed:20101266 |
| Chain | Residue | Details |
| A | THR355 | |
| A | SER283 | |
| A | SER285 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine; by CDK1 => ECO:0000269|PubMed:20622854, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER120 |
