3JZK
crystal structure of MDM2 with chromenotriazolopyrimidine 1
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | E3 ubiquitin-protein ligase Mdm2 | polymer | 96 | 11156.1 | 1 | UniProt (Q00987) Pfam (PF02201) In PDB | Homo sapiens (human) | p53-binding protein Mdm2, Oncoprotein Mdm2, Double minute 2 protein, Hdm2 |
2 | A | (6R,7S)-6,7-bis(4-bromophenyl)-7,11-dihydro-6H-chromeno[4,3-d][1,2,4]triazolo[1,5-a]pyrimidine | non-polymer | 536.2 | 1 | Chemie (YIN) | |||
3 | water | water | 18.0 | 45 | Chemie (HOH) |
Sequence modifications
A: 17 - 111 (UniProt: Q00987)
PDB | External Database | Details |
---|---|---|
Gly 16 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 11156.1 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 536.2 | |
All* | Total formula weight | 11692.3 |