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3HRB

p38 kinase Crystal structure in complex with small molecule inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AMitogen-activated protein kinase 14polymer35941212.01UniProt (Q16539)
Pfam (PF00069)
In PDB
Homo sapiens (human)Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha, Cytokine suppressive anti-inflammatory drug-binding protein, CSAID-binding protein, CSBP, MAX-interacting protein 2, MAP kinase MXI2, SAPK2A
2A[3-amino-2-(2-methylphenyl)-1-oxidopyridin-4-yl](2,4-difluorophenyl)methanonenon-polymer340.31Chemie (I39)
3waterwater18.0180Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight41212.0
Non-Polymers*Number of molecules1
Total formula weight340.3
All*Total formula weight41552.3
*Water molecules are not included.

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PDB entries from 2024-05-01

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