3E4C
Procaspase-1 zymogen domain crystal structure
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Caspase-1 | polymer | 302 | 33797.4 | 2 | UniProt (P29466) Pfam (PF00656) In PDB | Homo sapiens (Human) | CASP-1, Interleukin-1 beta convertase, IL-1BC, Interleukin-1 beta-converting enzyme, IL-1 beta-converting enzyme, ICE, p45, Caspase-1 subunit p20, Caspase-1 subunit p10 |
| 2 | B | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | water | water | 18.0 | 136 | Chemie (HOH) |
Sequence modifications
A, B: 104 - 404 (UniProt: P29466)
| PDB | External Database | Details |
|---|---|---|
| Gln 103 | - | expression tag |
| Ala 285 | Cys 285 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 67594.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 24.3 | |
| All* | Total formula weight | 67619.1 |
