3BC3

Exploring inhibitor binding at the S subsites of cathepsin L

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Cathepsin L heavy and light chains	polymer	220	24223.7	2	UniProt (P07711) Pfam (PF00112) In PDB	Homo sapiens (human)	(EC 3.4.22.15) (Major excreted protein) (MEP)
2	A, B	S-benzyl-N-(biphenyl-4-ylacetyl)-L-cysteinyl-N~5~-(diaminomethyl)-D-ornithyl-N-(2-phenylethyl)-L-tyrosinamide	non-polymer		830.0	2	Chemie (OPT)
3		water	water		18.0	423	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	48447.4
Non-Polymers*	Number of molecules	2
	Total formula weight	1660.1
All*	Total formula weight	50107.5

*Water molecules are not included.