3B9K

Crystal structure of CD8alpha-beta in complex with YTS 156.7 FAB

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	L, C	Fab Light Chain	polymer	213	23459.1	2		rattus rattus (rat)
2	H, D	Fab Heavy chain	polymer	214	22864.3	2		rattus rattus (rat)
3	A, E	T-cell surface glycoprotein CD8 alpha chain	polymer	131	14783.9	2	UniProt (P01731) Pfam (PF07686) In PDB	Mus musculus (mouse)	T-cell surface glycoprotein Lyt-2, CD8a antigen
4	B, F	T-cell surface glycoprotein CD8 beta chain	polymer	125	14080.1	2	UniProt (P10300) Pfam (PF07686) In PDB	Mus musculus (mouse)	T-cell surface glycoprotein Lyt-3, T-cell membrane glycoprotein Ly-3, Lymphocyte antigen 3, CD8b antigen
5	A, E	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
6		water	water		18.0	36	Chemie (HOH)

Sequence modifications

A, E: 1 - 124 (UniProt: P01731)

PDB	External Database	Details
Ser 125	-	expression tag
Ala 126	-	expression tag
Asp 127	-	expression tag
Leu 128	-	expression tag
Val 129	-	expression tag
Pro 130	-	expression tag
Arg 131	-	expression tag

B, F: 1 - 117 (UniProt: P10300)

PDB	External Database	Details
Ser 118	-	expression tag
Ser 119	-	expression tag
Ala 120	-	expression tag
Asp 121	-	expression tag
Leu 122	-	expression tag
Val 123	-	expression tag
Pro 124	-	expression tag
Arg 125	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	150374.9
Non-Polymers*	Number of molecules	2
	Total formula weight	442.4
All*	Total formula weight	150817.3

*Water molecules are not included.