2Z80
Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Toll-like receptor 2, Variable lymphocyte receptor B | polymer | 353 | 39710.2 | 2 | UniProt (O60603) UniProt (Q4G1L2) Pfam (PF00560) Pfam (PF13855) In PDB | Homo sapiens (human inshore hagfish) | Toll/interleukin-1 receptor-like protein 4, CD282 antigen |
2 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
3 | water | water | 18.0 | 263 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 284 (UniProt: O60603)
A, B: 290 - 353 (UniProt: Q4G1L2)
PDB | External Database | Details |
---|---|---|
Ser 285 | - | linker |
Arg 286 | - | linker |
Asn 287 | - | linker |
Gln 288 | - | linker |
Leu 289 | - | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 79420.3 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 221.2 | |
All* | Total formula weight | 79641.5 |