2Z80

Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001817	biological_process	regulation of cytokine production
A	0002224	biological_process	toll-like receptor signaling pathway
A	0002237	biological_process	response to molecule of bacterial origin
A	0002755	biological_process	MyD88-dependent toll-like receptor signaling pathway
A	0004888	molecular_function	transmembrane signaling receptor activity
A	0006955	biological_process	immune response
A	0016021	cellular_component	integral component of membrane
A	0034134	biological_process	toll-like receptor 2 signaling pathway
A	0045087	biological_process	innate immune response
B	0001817	biological_process	regulation of cytokine production
B	0002224	biological_process	toll-like receptor signaling pathway
B	0002237	biological_process	response to molecule of bacterial origin
B	0002755	biological_process	MyD88-dependent toll-like receptor signaling pathway
B	0004888	molecular_function	transmembrane signaling receptor activity
B	0006955	biological_process	immune response
B	0016021	cellular_component	integral component of membrane
B	0034134	biological_process	toll-like receptor 2 signaling pathway
B	0045087	biological_process	innate immune response

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:15173186, ECO:0000269|PubMed:17889651

Chain	Residue	Details
A	ASN114
A	ASN199
B	ASN114
B	ASN199

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