2W0J

Crystal structure of Chk2 in complex with NSC 109555, a specific inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	SERINE/THREONINE-PROTEIN KINASE CHK2	polymer	323	36562.2	1	UniProt (O96017) Pfam (PF00069) In PDB	HOMO SAPIENS (HUMAN)	CHECKPOINT KINASE 2, CDS1
2	A	4,4'-DIACETYLDIPHENYLUREA-BIS(GUANYLHYDRAZONE)	non-polymer		408.5	1	Chemie (ZAT)
3	A	NITRATE ION	non-polymer		62.0	1	Chemie (NO3)
4		water	water		18.0	133	Chemie (HOH)

Sequence modifications

A: 209 - 209 (PDB: 2W0J)
A: 210 - 531 (UniProt: O96017)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	36562.2
Non-Polymers*	Number of molecules	2
	Total formula weight	470.5
All*	Total formula weight	37032.7

*Water molecules are not included.