2M20
EGFR transmembrane - juxtamembrane (TM-JM) segment in bicelles: MD guided NMR refined structure.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Epidermal growth factor receptor | polymer | 60 | 6779.3 | 2 | UniProt (P00533) Pfam (PF21314) In PDB | Homo sapiens (human) | Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1 |
Sequence modifications
A, B: 1 - 56 (UniProt: P00533)
PDB | External Database | Details |
---|---|---|
Leu 9 | Met 650 | engineered mutation |
Ile 27 | Met 668 | engineered mutation |
Lys 57 | - | expression tag |
Leu 58 | - | expression tag |
Trp 59 | - | expression tag |
Ser 60 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 13558.5 | |
All* | Total formula weight | 13558.5 |