2LGC
Joint NMR and X-ray refinement reveals the structure of a novel dibenzo[a,d]cycloheptenone inhibitor/p38 MAP kinase complex in solution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Mitogen-activated protein kinase 14 | polymer | 359 | 41208.1 | 1 | UniProt (Q16539) Pfam (PF00069) In PDB | Homo sapiens (human) | MAP kinase 14, MAPK 14, Cytokine suppressive anti-inflammatory drug-binding protein, CSAID-binding protein, CSBP, MAP kinase MXI2, MAX-interacting protein 2, Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha, SAPK2A |
Sequence modifications
A: 2 - 354 (UniProt: Q16539)
| PDB | External Database | Details |
|---|---|---|
| Ser -4 | - | expression tag |
| His -3 | - | expression tag |
| Met -2 | - | expression tag |
| Leu -1 | - | expression tag |
| Glu 0 | - | expression tag |
| Met 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41208.1 | |
| All* | Total formula weight | 41208.1 |
