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2IYF

The crystal structure of macrolide glycosyltransferases: A blueprint for antibiotic engineering

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BOLEANDOMYCIN GLYCOSYLTRANSFERASEpolymer41545392.02UniProt (Q3HTL6)
Pfam (PF06722)
UniProt (by SIFTS) (Q53685)
In PDB
STREPTOMYCES ANTIBIOTICUSOLED
2A, BERYTHROMYCIN Anon-polymer733.92Chemie (ERY)
3A, BURIDINE-5'-DIPHOSPHATEnon-polymer404.22Chemie (UDP)
4BMAGNESIUM IONnon-polymer24.31Chemie (MG)
5waterwater18.0604Chemie (HOH)
Sequence modifications
A, B: 0 - 414 (UniProt: Q3HTL6)
PDBExternal DatabaseDetails
Pro 54Ala 55conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight90784.0
Non-Polymers*Number of molecules5
Total formula weight2300.5
All*Total formula weight93084.5
*Water molecules are not included.

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PDB entries from 2024-04-24

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