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2IYF

The crystal structure of macrolide glycosyltransferases: A blueprint for antibiotic engineering

Summary for 2IYF
Entry DOI10.2210/pdb2iyf/pdb
DescriptorOLEANDOMYCIN GLYCOSYLTRANSFERASE, ERYTHROMYCIN A, URIDINE-5'-DIPHOSPHATE, ... (5 entities in total)
Functional Keywordsantibiotic resistance, glycosylation, glycosyltransferase, enzyme, macrolide, transferase, carbohydrate
Biological sourceSTREPTOMYCES ANTIBIOTICUS
Total number of polymer chains2
Total formula weight93084.50
Authors
Bolam, D.N.,Roberts, S.M.,Proctor, M.R.,Turkenburg, J.P.,Dodson, E.J.,Martinez-Fleites, C.,Yang, M.,Davis, B.G.,Davies, G.J.,Gilbert, H.J. (deposition date: 2006-07-17, release date: 2007-03-27, Last modification date: 2013-08-07)
Primary citationBolam, D.N.,Roberts, S.M.,Proctor, M.R.,Turkenburg, J.P.,Dodson, E.J.,Martinez-Fleites, C.,Yang, M.,Davis, B.G.,Davies, G.J.,Gilbert, H.J.
The Crystal Structure of Two Macrolide Glycosyltransferases Provides a Blueprint for Host Cell Antibiotic Immunity.
Proc.Natl.Acad.Sci.USA, 104:5336-, 2007
Cited by
PubMed: 17376874
DOI: 10.1073/PNAS.0607897104
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.7 Å)
Structure validation

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