2IYF
The crystal structure of macrolide glycosyltransferases: A blueprint for antibiotic engineering
Summary for 2IYF
Entry DOI | 10.2210/pdb2iyf/pdb |
Descriptor | OLEANDOMYCIN GLYCOSYLTRANSFERASE, ERYTHROMYCIN A, URIDINE-5'-DIPHOSPHATE, ... (5 entities in total) |
Functional Keywords | antibiotic resistance, glycosylation, glycosyltransferase, enzyme, macrolide, transferase, carbohydrate |
Biological source | STREPTOMYCES ANTIBIOTICUS |
Total number of polymer chains | 2 |
Total formula weight | 93084.50 |
Authors | Bolam, D.N.,Roberts, S.M.,Proctor, M.R.,Turkenburg, J.P.,Dodson, E.J.,Martinez-Fleites, C.,Yang, M.,Davis, B.G.,Davies, G.J.,Gilbert, H.J. (deposition date: 2006-07-17, release date: 2007-03-27, Last modification date: 2013-08-07) |
Primary citation | Bolam, D.N.,Roberts, S.M.,Proctor, M.R.,Turkenburg, J.P.,Dodson, E.J.,Martinez-Fleites, C.,Yang, M.,Davis, B.G.,Davies, G.J.,Gilbert, H.J. The Crystal Structure of Two Macrolide Glycosyltransferases Provides a Blueprint for Host Cell Antibiotic Immunity. Proc.Natl.Acad.Sci.USA, 104:5336-, 2007 Cited by PubMed: 17376874DOI: 10.1073/PNAS.0607897104 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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