2IHM
Polymerase mu in ternary complex with gapped 11mer DNA duplex and bound incoming nucleotide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | T, U | 5'-D(*CP*GP*GP*CP*AP*AP*TP*AP*CP*TP*G)-3' | polymer | 11 | 3358.2 | 2 | |||
| 2 | P, Q | 5'-D(*CP*AP*GP*TP*AP*T)-3' | polymer | 6 | 1808.2 | 2 | |||
| 3 | D, E | 5'-D(P*GP*CP*CP*G)-3' | polymer | 4 | 1191.8 | 2 | |||
| 4 | A, B | DNA polymerase mu | polymer | 360 | 40612.0 | 2 | UniProt (Q9JIW4) Pfam (PF14716) Pfam (PF10391) Pfam (PF14792) Pfam (PF14791) In PDB | Mus musculus (house mouse) | Pol Mu |
| 5 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 6 | A, B | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
| 7 | A | 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE | non-polymer | 466.2 | 2 | Chemie (D3T) | |||
| 8 | water | water | 18.0 | 183 | Chemie (HOH) |
Sequence modifications
A, B: 137 - 496 (UniProt: Q9JIW4)
| PDB | External Database | Details |
|---|---|---|
| Val 386 | Ala 386 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 93940.6 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1049.9 | |
| All* | Total formula weight | 94990.5 |
